The Laboratory for Inborn Errors of Metabolism (PLIEM) is situated in the Centre for Human Metabonomics (CHM) at the Potchefstroom Campus of the North-West University. The Scientists at the CHM are well known for their expertise and many years of experience in the field of inborn errors of metabolism (IEM) and have provided a diagnostic service to both the public and private health sector since 1983.
The CHM is an active research contributor to the field of inborn errors of metabolism and has published many papers in peer reviewed journals over the past three decades and also has a formal relationship with the metabolic laboratory of the University of Amsterdam, a world renowned institution in the field of metabolic medicine.
Prof. L.J. Mienie is the head of the laboratory and initiated PLIEM. Prof Mienie and his team of medical scientists specialize in the identification of inherited / congenital metabolic defects, neurotoxicology of zenobiotics and are collaborating authors of various research articles. PLIEM further collaborates with internationally acclaimed laboratories in the Netherlands, Sweden, Belgium, Australia and the USA. Since 1983, national and international (e.g. Kenya, Namibia and Mauritius) paediatricians and physicians refer different specimens of patients (babies, infants, children and adults) with possible genetic disorders, to PLIEM for metabolic screening. The lab also partakes in an international external quality control program for metabolic disorders (ERNDIM), to assure service of the highest quality. The members of the lab take part in international training programs and present their research and knowledge at national and international scientific conferences and CPD lectures.